Pathogen inactivation/reduction of platelet concentrates: turning theory into practice
نویسندگان
چکیده
منابع مشابه
Economics of pathogen inactivation technology for platelet concentrates in Japan.
Residual risk of transmitting recognized and emerging blood-borne pathogens via blood transfusion in Japan persists despite advances in blood safety screening. The INTERCEPT Blood System (IBS) for platelets was developed to inactivate a broad spectrum of pathogens to reduce the risk of transfusion-transmitted infections. In this study we assessed the economic impact of the IBS on platelet trans...
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Whereas the reduction of transfusion related viral transmission has been a priority during the last decade, bacterial infection transmitted by transfusion still remains associated to a high morbidity and mortality, and constitutes the most frequent infectious risk of transfusion. This problem especially concerns platelet concentrates because of their favorable bacterial growth conditions. This ...
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Besides the current efforts devoted to microbial risk reduction, pathogen inactivation technologies promise reduction of the residual risk of known and emerging infectious agents. A novel pathogen reduction process for platelets, the THERAFLEX UV-Platelets system, has been developed and is under clinical evaluation for its efficacy and safety. In addition, proof of principle has been shown for ...
متن کاملTackling health inequalities: turning policy into practice?
Acknowledgements We are grateful to the authors of the papers commissioned for the seminars. We also wish to thank all the seminar participants who commented on the papers and provided valuable insights from their own experiences. The Health Development Agency (www.hda.nhs.uk) is the national authority and information resource on what works to improve people's health and reduce health inequalit...
متن کاملComparative Study of Four Platelet-Rich Plasma Methods for Preparing Platelet Concentrates
Background: Platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. Platelet concentrates can be prepared by the apheresis method or from the whole blood using the Buffy-coat or Platelet-rich plasma methods. The purpose of this study was to compare four variations of platelet-rich plasma method based on double...
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ژورنال
عنوان ژورنال: ISBT Science Series
سال: 2010
ISSN: 1751-2816,1751-2824
DOI: 10.1111/j.1751-2824.2010.01417.x